Discovering the secrets of cell membrane
A new study by the Hospital del Mar Research Institute has revealed that the proteins located in the cell membrane function as hidden portals that can alter the behavior of cells. This find promises to open new opportunities for pharmacological intervention.
International collaboration in research
The project was attended by institutions from various countries, including Spain, Switzerland, the United Kingdom, and many others. This international cooperation has been essential to achieving an unprecedented level of detail through computer simulations.
A look at the atòmica
Researchers have managed to observe, in real time, the interaction between the lipids of the membrane and the receptors coupled with proteins G (GPCR). These interactions provide a new perspective on how cell functions can be regulated, revealing paths that had previously gone unnoticed.
The key role of GPCR
GPCRs are essential in modern pharmacology, as about a third of the FDAs approved by these receptors. The new information on its operation can accelerate the design of more efficient drugs.
Future perspectives in GPCR research
The current study is based on 190 experiments collected from 60% of known GPCRs, and continues to explore how these proteins modulate cells. Researchers have discovered new accesses, which are only visible through simulations, which can facilitate the development of innovative treatments.
The importance of selectivity in medicines
Thanks to this research, more accurate targets can be identified, which could allow the creation of more selective drugs, thus minimizing the side effects. This opens the door to a more advanced approach to the treatment of various pathologies.
Access to potential research and applications
The results of this work are now available online, making it easier to use this information in the design of new medicines for a wide range of diseases. The promise of a future in which medicine becomes more personalized and effective is closer than ever.
